A laboratory tool known as a reciprocating dissolution tester is used to assess the speed and volume of drug release from solid dosage forms like tablets, capsules, and granules. It is frequently used for quality control and research in the pharmaceutical sector. A collection of glass jars with a dissolving media within that replicates the physiological circumstances of the digestive tract and a reciprocating holder holding the solid dosage form under test make up the device. To mimic gastrointestinal motility and improve medication release, the holder pushes the dosage form up and down in the dissolution medium at a regulated pace and frequency.
Various analytical methods, such as spectrophotometry or high-performance liquid chromatography (HPLC), are used throughout the test to assess the amount of medication released from the solid dosage form into the dissolution media over time. The reciprocating dissolution tester has a number of benefits over conventional dissolution testers, including better mixing and gastrointestinal tract modelling. As a result, drug release profiles become more precise and repeatable, which is crucial for assuring the reliability and security of pharmaceutical products.
The reciprocating dissolution tester, in general, is a useful instrument for researchers and quality control specialists in the pharmaceutical business as well as in other industries that need to monitor drug release from solid dosage forms.
| Model | ERD-07 |
| Material of Construction | SS 316 |
| Water Bath | Clear acrylic moulded water bath |
| Bath capacity | 44 litres |
| No. of rows | 6 |
| Vessel capacity (ml) | 300 |
| Reciprocating height (mm) | 100 |
| No. of dips rate (dpm) | 5 to 50 |
| Accuracy (deg C) | 0.2 |
| Controlled temperature range (deg C) | 30 to 40 |
| Display | Touch screen |
| Motor | Single shaft Motor 10 kg cm |
| Heater | 1000 Watts, 230 V AC, S. S 304 |
| Mains fuse | 1 Amp |
| Heater fuse | 6 Amp |
| Dimension (L X W X H) | 795 X 675 X 780 mm |
Ans - A gadget called a reciprocating dissolving tester is used to gauge how quickly pharmaceutical items like tablets and capsules dissolve. It compares the medication release rates of various formulations by replicating the patient's gastrointestinal environment.
Ans - In comparison to conventional dissolve testing, using a reciprocating dissolution tester can offer a more accurate and trustworthy evaluation of drug release rates. Because the data may be achieved more quickly and with more accuracy, it also enables a more effective product development process.
Ans - Tests for the reciprocating dissolution of a variety of materials, such as tablets, capsules, and granules, are available.
Ans - The speed and direction of the test medium's reciprocating motion are commonly controlled by an automated system that operates a reciprocating dissolution tester. Additionally, this system regulates the test medium's temperature, pH, and other characteristics.
Ans - With results within 5% to 10% of those obtained from conventional dissolving tests, reciprocating dissolution tester results are often highly accurate.
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